The conserved head structure, the membrane portion and the peripheral stalk (or stalks) together could have formed a translocase that coupled ATP hydrolysis to the transfer of RNA and/or proteins ...

ATP is the primary energy currency in cells. It consists of an adenine base, a ribose sugar, and three phosphate groups. The hydrolysis of ATP releases energy that is used to drive various cellular ...

J-domain proteins (JDPs) coevolved with Hsp70s to trigger ATP hydrolysis and catalytically upload various substrate polypeptides in need to be structurally modified by the chaperone. Here, we measured ...